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simplify [p (p+1) (p+2) (p+3) (p+q)^3] - 4[ p^2 (p+1) (p+2) (p+q)^2 (p+q+3) ] +6[ p^3 (p+1) (p+q) (p+q+2) (p+q+3)] -3[ p^4 (p+q+1) (p+q+2) (p+q+3)]
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